ライフサイエンスソリューションズ株式会社

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Company Profile

Name
Life Science Solutions Inc.
Paid in Capital
9.8 mil. JPY
President, CEO
Kohei Shiba, Ph.D.
Group Company
Reifycs Analytical Inc.
Lines of Business
Sales, Application support, and Consultation for analytical
science system and peripheral systems and CRO
Main Customers
Top 30 Pharmaceutical companies in Japan
(mainly R&D division)
・Takeda Pharmaceutical, Astellas Pharma, Daiichi Sankyo
Pharma, Chugai Pharma (Roche)
Material suppliers for liquid pharmaceuticals
・Terumo, Nipro, Ajinomoto Foods
Universities, National Institutes
・Osaka University, Univ. of Tokyo, NIHS
Main Collaborators
Hardware supplier, CRO
Refeyn Ltd. (UK)
Cordouan Technologies(France)

About me

  • Kohei Shiba, Ph. D.
    (志波 公平、博士(工学))
  • Life Science Solutions, Inc.
  • President, CEO

Background

2000. Mar.
Graduated Master degree at Applied Chemistry, Faculty of engineering, Nagasaki University
2000. Apr.
Joined Sysmex Corporation
2007. Apr.
Admitted at System life science, Faculty of Engineering, Kyushu University
2010. Jun.
Got doctor degree at System life science, Faculty of Engineering, Kyushu University
2010. Sep.
Joined Malvern Instruments, a group of Spectris Ltd. Innovation Products Specialist, Asia Pacific
2017. Jan.
Changed company name to Malvern Panalytical, a group of Spectris Co. Ltd. Bioscience Specialist, APAC, co-positioned of Pharma & Food business sector leader
2018. Jan.
Pharma & Food business development manager, North Pacific
2020. Feb.
Life Science Solutions Inc. President, CEO

Awards:

>Hot Article Award of Analytical Sciences, 2010.6. Entitled “Polydispersity as a parameter for indicating the thermal stability of proteins by dynamic light scattering.”

>Young Scientist Award, Material Research of Science of Japan, 2009. Entitled “Polydispersity as a parameter for evaluating the binding constant of protein to small ligands by dynamic light scattering.”

Publications (Main part; not included congress publications and local publications):

Inhibition of the Functional Interplay between Endoplasmic Reticulum (ER) Oxidoreduclin-1_(Ero1_)
and Protein-disulfide Isomerase (PDI) by the Endocrine Disruptor Bisphenol A.
Journal of Biol.Chem., 289 (39): 27004-28018 (2014)
Masaki Okumura, Hiroshi Kadokura**, Shoko Hashimoto, Katsuhide Yutani, Shingo Kanemura,
Takaaki Hikima, Yuji Hidaka, Len Ito, Kohei Shiba, Shoji Masui, Daiki Imai, Susumu Imaoka,
Hiroshi Yamaguchi, and Kenji Inaba

Structural stabilization of protein 4.1R FERM domain upon binding to apo-calmodulin: Novel
insights into the biological significance of the calcium-independent binding of calmodulin to
protein 4.1R. Biochem. J. 440(3): 367-374 (2011).
Wataru Nunomura, Daisuke Sasakura, Kohei Shiba, Shigeyoshi Nakamura,
Shin-ichi Kidokoro, Yuichi Takakuwa

*Polydispersity as a parameter for indicating the thermal stability of proteins by dynamic light
scattering.  Anal. Sci., 26 (10): 659-663, (2010)
Kohei Shiba, Takuro Niidome, Etsuko Katoh, Hongyu Xiang, Lu Han, Takeshi Mori,
Yoshiki Katayama

Structural advantage of dendritic poly(L-lysine) for gene delivery into cells, Bioorg. Med. Chem.,
15, 526-532 (2007)
Masato Yamagata, Takahito Kawano, Kohei Shiba, Takeshi Mori, Yoshiki Katayama,
Takuro Niidome

Characterization of a recombinant C-type lectin, rCEL-IV, expressed in Escherichia coli cells
using a synthetic gene. Biochim Biophys Acta. 2006 Mar;1760(3):318-25. Epub 2006 Feb 13.
Hatakeyama T, Hozawa T, Hirotani I, Tsuda N, Kusunoki M, Shiba K.

Characterization of recombinant CEL-I, a GalNAc-specific C-type lectin, expressed in Escherichia
coli using an artificial synthetic gene. J Biochem. 2004 Jan;135(1):101-7.
Hatakeyama T, Shiba K, Matsuo N, Fujimoto T, Oda T, Sugawara H, Aoyagi H.

Amino acid sequence and carbohydrate-binding analysis of the N-acetyl-D-galactosamine-specific
C-type lectin, CEL-I, from the Holothuroidea, Cucumaria echinata. Biosci Biotechnol Biochem. 2002
Jan;66(1):157-63.
Hatakeyama T, Matsuo N, Shiba K, Nishinohara S, Yamasaki N, Sugawara H, Aoyagi H.